Relationship Between Body Composition and Insulin Resistance Evaluated by the Triglyceride Glucose (TyG) Index: A Retrospective Study Among Chinese Population
Authors' conclusion
The TyG index correlates with body composition parameters of FFMI and PBF as well as HOMA-IR potentially making it a convenient marker of metabolic risk.
Study context
- Population
- Chinese adults with body composition measured by bioelectrical impedance analysis, January 2018–December 202112,186 initially enroled
- Participants
- 4,061 adults
- Outcome
- Relationship between body composition and IR assessed by the TyG index
Main finding
As reported in the abstract
Correlation of body composition with TyG index
AUC of combined fat-free mass index (FFMI) and percent body fat (PBF) for insulin resistance (IR) diagnosis, women
0.718
AUC of combined FFMI and PBF for IR diagnosis, men
0.661
Observational data: associations, not effects.
Further findings
Body composition by age (≥50 vs younger)
- Older women: significantly higher BMI, PBF, fat mass (FM), fat mass index (FMI), FFMI, HOMA-IR and TyG index, lower fat-free mass (FFM) vs younger women
- Older men: significantly lower BMI, FM, FFM, FFMI, HOMA-IR and TyG index vs younger men
Original publication
Relationship Between Body Composition and Insulin Resistance Evaluated by the TyG Index: A Retrospective Study Among Chinese Population. Clin Endocrinol (Oxf). Published 1 December 2024. doi:10.
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