Low Skeletal Muscle Mass Accompanied by Abdominal Obesity Additively Increases the Risk of Incident Type 2 Diabetes
Authors' conclusion
Low skeletal muscle mass and its coexistence with abdominal obesity additively increased the risk of incident type 2 diabetes independent of the glycometabolic parameters.
Study context
- Population
- Diabetes-free Koreans with ≥2 annual or biannual health checkups; SMI by bioelectrical impedance, adjusted for body weight
- Participants
- 36,304 participants
- Exposure
- Low SMI and presarcopenic obesity vs reference body composition
- Outcome
- Incident T2D
- Follow-up
- 7-year follow-up
Methodological detailslongitudinal
- Longitudinal
Main finding
As reported in the abstract
Adjusted hazard ratio (95% CI)
Lowest sex-specific SMI tertilevs Highest tertilefully adjusted model
1.31(1.18–1.45)
Presarcopenic obesity vs Normalalso increasedvs presarcopenia alone or abdominal obesity alone
1.57(1.42–1.73)
- Cumulative incidence of diabetes
- 9.1%
Observational data: associations, not effects.
Original publication
Low Skeletal Muscle Mass Accompanied by Abdominal Obesity Additively Increases the Risk of Incident Type 2 Diabetes. J Clin Endocrinol Metab. Published 17 November 2022. doi:10.
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