Referral to Definitive Surgical Treatment in Cushing's Syndrome – An Odyssey That Requires Attention
Authors' conclusion
There were delays from initial referral to definitive surgical treatment of CS.
Study context
- Population
- Adults diagnosed with cushing's syndrome (CS) who underwent definitive surgery, January 2018–December 2019; 37 pituitary CS and 34 adrenal CS
- Participants
- 71 adults
- Exposure
- Direct referral to specialised endocrine surgical centre vs referral via non-surgical endocrinology centre
- Outcome
- Time from initial referral to definitive surgical management in CS
Methodological detailsmulticentre, five specialised endocrine surgical centres
- Multicentre
- Five specialised endocrine surgical centres
Main finding
As reported in the abstract
Time from initial referral to definitive surgery
| Group | Value | Pituitary CS | Adrenal CS |
|---|---|---|---|
| Direct referral | median 196 days | 187 days | 252 days |
| Via non-surgical endocrinology centre | median 253 days | 249 days | 346 days |
Value
Direct referralmedian 196 days
Via non-surgical endocrinology centremedian 253 days
Pituitary CS
Direct referral187 days
Via non-surgical endocrinology centre249 days
Adrenal CS
Direct referral252 days
Via non-surgical endocrinology centre346 days
Days
- Overall median time from all initial referrals to definitive surgery, pituitary CS
- 211
- Overall median time from all initial referrals to definitive surgery, adrenal CS
- 253
Observational data: associations, not effects.
Further findings
- Time from initial primary care referral to specialised endocrine surgical centre — Referred via a non-surgical endocrinology centre
- median 159 days
- Time from initial primary care referral to specialised endocrine surgical centre: Direct referral median 56 days
Original publication
Referral to Definitive Surgical Treatment in Cushing's Syndrome – An Odyssey That Requires Attention. Clin Endocrinol (Oxf). Published 10 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →