Reduction in the prevalence of methicillin‐resistant Staphylococcus aureus in tissue and wound swab samples taken from outpatients attending a specialist diabetic foot clinic 2005–2021
Authors' conclusion
Prevalence of MRSA in DFU infections treated as outpatients is decreasing in line with falls in hospital acquired blood-borne infections and with overall hospital MRSA incidence. This is likely a reflection of the combination of interventions, including stringent antibiotic prescribing and decolonisation strategies. Reduction in prevalence should have positive impact on outcomes in people living with diabetes, reducing the complication of osteomyelitis and necessity for long-term antibiotic administration.
Study context
- Population
- Outpatients with diabetes and DFUs attending a specialist multidisciplinary foot clinic, July 2005–July 20216,312 swabs
- Participants
- 1,916 outpatients
- Outcome
- Annual change in prevalence of MRSA from tissue and wound swab samples from DFUs
- Follow-up
- 2005–2021
Methodological detailssingle-centre, specialist multidisciplinary foot clinic
- Single-centre
- Specialist multidisciplinary foot clinic
Main finding
As reported in the abstract
Peak in 2008
14.6%
n = 38
2013
5.2%
n = 20
Did not exceed, 2015 to 2021
4%
n = 6
Observational data: associations, not effects.
Further findings
Methicillin resistant Staphylococcus aureus (MRSA) positive isolates from DFU swabs
- MRSA positive isolates
- 406
- Individuals with MRSA positive isolates
- 185
- Hospital-acquired infections (HAIs)
- 22
- Community-acquired infections (CAIs)
- 159
≥3 risk factors for MRSA among MRSA-positive individuals, 2010 to 2021 (n = 71)
- ≥3 risk factors
- 52% (n = 37)
Hospital MRSA
- Lowest in 2021
- n = 211
- 2007
- n = 880
- Fall from 2007 to 2021
- 76%
Incidence of MRSA HAI, 2015 to 2021
- Lowest, 2020
- 5.4% (n = 14)
- Highest, 2018
- 11.5% (n = 41)
Original publication
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