Reduced incidence of cardiovascular disease in patients with type 2 diabetes through the integrated improvement of diabetes care by comparing two prospective observational cohorts in real-world clinical practice (JDDM 72)
Main finding · Composite of CVD onset and deathResult — go to the resultHazard ratio 0.73 95% CI 0.62–0.86Authors' conclusion
The significant reduction of Cohort 2 for cardiovascular disease independent of the baseline covariates suggests an integrated effect delivered by the recent treatment advances.
Study context
- Population
- Patients with T2D in real-world clinical practice
- Participants
- 3,919 vs 3,286
- Exposure
- Cohort 2 vs Cohort 1
- Cohort 2n = 3,919
- Cohort 1n = 3,286reference
- Outcome
- Composite of:
- Onset of CVD
- Death
- Follow-up
- 8-year follow-up
Methodological detailstwo independent cohorts, Cox proportional hazards analysis adjusted for covariates
- Two independent cohorts
- Cox proportional hazards analysis adjusted for covariates
Main finding
Composite of:
Hazard ratio
0.73
95% CI 0.62–0.86
Events by group
Cohort 2vs Cohort 1
HR 0.73 (95% CI 0.62–0.86)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Cohort 2 | Cohort 1 | HR (95% CI) | |
|---|---|---|---|---|
| CVD · 8-year follow-up | 4.1% | 8.2% | 0.64 (0.52–0.79) | |
| 0.512Hazard ratio (log scale) |
- CVD: significant reduction also independent of accumulation of five risks
Original publication
Reduced incidence of cardiovascular disease in patients with type 2 diabetes through the integrated improvement of diabetes care by comparing two prospective observational cohorts in real-world clinical practice (JDDM 72). Diabetes Res Clin Pract. Published 21 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →