Comparing the effects of time-restricted eating on glycaemic control in people with type 2 diabetes with standard dietetic practice: A randomised controlled trial
Primary result · Change in HbA1cResult — go to the resultDifference −0.11 % 95% CI −0.50% to 0.28%Authors' conclusion
When individualised dietary guidance is not available, effective, and/or suitable, TRE may be an alternative dietary strategy to improve glycaemic control in people with Type 2 diabetes mellitus.
Study context
- Population
- Adults (35–65 y) with T2D and overweight/obesity (HbA1c ≥6.5% (48 mmol/mol), BMI ≥25-≤40 kg/m²); six-month intervention, four consultations over four months43 completed
- Participants
- 51 adults
- Comparison
- Time-restricted eating vs individualised dietetic guidance
- Primary endpoint
- Change in HbA1c; non-inferiority margin 0.3% (4 mmol/mol)
- Follow-up
- Six months
Methodological detailsparallel groups, non-inferiority
- Parallel groups
- Non-inferiority
Primary result
Change in HbA1c
Difference
−0.11 %
95% CI −0.50% to 0.28%
Change by group
Time-restricted eating (TRE)
−0.4%
DIET
−0.3%
TREvs DIET
difference −0.11 % (95% CI −0.50% to 0.28%)
As reported in the abstract
- HbA1c reduced overall, with no group or interaction effects
- P = 0.002
Further findings
kg
| Outcome | TRE | DIET |
|---|---|---|
| Change in body mass | −1.7 | −1.2 |
- Change in body mass — Body mass reduced in both groups via ∼900 kJ/d spontaneous energy reduction
- P<0.001
- Self-reported adherence · higher with TRE
- P < 0.001
Original publication
Comparing the effects of time-restricted eating on glycaemic control in people with type 2 diabetes with standard dietetic practice: A randomised controlled trial. Diabetes Res Clin Pract. Published 15 October 2024. doi:10. 1016/ j. diabres. 2024. 111893
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