Childhood maltreatment, adulthood obesity and incident type 2 diabetes: a retrospective cohort study using UK Biobank
Authors' conclusion
People who recalled maltreatment in childhood are at higher risk of T2D in adulthood, partly due to obesity.
Study context
- Population
- UK Biobank participants who completed the childhood maltreatment questions; one-third reported some form of maltreatment
- Participants
- 153,601 completed maltreatment questions
- Exposure
- Recalled childhood maltreatment vs no maltreatment
- Outcome
- Adult obesity and incident T2D (and BMI)
Methodological detailsUK Biobank, decomposition analysis
- UK Biobank
- Decomposition analysis
Main finding
As reported in the abstract
≥3 types of childhood maltreatment vs Not maltreatedEstimate (95% CI)
Obesity
OR 1.55(1.47–1.63)
Incident T2D
HR 1.65(1.52–1.80)
Observational data: associations, not effects.
Further findings
Excess T2D risk attributable to body mass index (BMI) (decomposition analysis)
- Excess T2D risk among maltreated could be reduced if BMI comparable to non-maltreated
- 39%
- Assuming causality
Original publication
Childhood maltreatment, adulthood obesity and incident type 2 diabetes: a retrospective cohort study using UK Biobank. Int J Obes (Lond). Published 15 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →