Real-world costs of obesity-related complications over eight years: a US retrospective cohort study in 28,500 individuals
Authors' conclusion
In a US real-world setting, the number of ORCs appears to be a cost driver in people with obesity, from the time of initial obesity classification and for at least the following 8 years.
Study context
- Population
- US adults (≥18 years) with BMI 30-<70 kg/m² between 1 January 2007 and 31 March 2012, continuous enrolment ≥1 year pre index and ≥8 years post index
- Participants
- 28,583 adults
- Exposure
- Number of obesity-related complications (ORCs) in baseline year
- No ORCsn = 12,686reference
- One ORCn = 7,242
- Two ORCsn = 4,180
- Three or more ORCsn = 4,475
- Outcome
- Annual total adjusted direct per-person healthcare costs
- Follow-up
- 8-year follow-up
Methodological detailslinked electronic medical records and administrative claims databases, 8-year follow-up
- Linked electronic medical records and administrative claims databases
- 8-year follow-up
Main finding
As reported in the abstract
Annual adjusted direct healthcare costs
- Annual adjusted direct healthcare costs increased with the number of ORCs and over the 8-year follow-up
Observational data: associations, not effects.
Further findings
Cost components at baseline
- Outpatient costs were the greatest contributor to baseline annual direct costs, irrespective of number of ORCs
Costs for specific ORCs, % increase year 1 to year 8
- CKD
- + 78.8%
- T2D
- + 47.8%
- Costs generally increased gradually over follow-up
Original publication
Real-world costs of obesity-related complications over eight years: a US retrospective cohort study in 28,500 individuals. Int J Obes (Lond). Published 18 September 2023. doi:10.
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