Failure to thrive in children with tubulopathies increases the risk of overweight later in life
Authors' conclusion
In conclusion, in our series, patients with tubulopathies presented an increased risk of overweight/obesity due to the FTT that can complicate these conditions.
Study context
- Population
- Children with renal tubulopathies first evaluated within the first 12 months of life (mean age 4.8 months ± 2.6 SDS); mean age at last follow-up 14.1 years ± 5.5 SDS
- Participants
- 26 children
- Exposure
- Failure to thrive (FTT) vs no FTT
- FTTn = 17
- Without FTTn = 9reference
- Outcome
- Overweight/obesity
Main finding
As reported in the abstract
FTT vs Without FTTOdds ratio (95% CI)P value
Overweight/obesity
9.4(1.3–67.6)
P = 0.026Adjusted for preterm birth and birth weight <10th percentile
23.3(1.95–279.4)
P = 0.01Observational data: associations, not effects.
Further findings
Prevalence of overweight/obesity (all patients)
- Overweight/obesity prevalence
- 73.1% (19/26)
- FTT prevalence
- 17 out of 26 (65.4%)
- Mean age at overweight/obesity onset
- 9.0 years ± 3.6 SDS
Original publication
Failure to thrive in children with tubulopathies increases the risk of overweight later in life. Int J Obes (Lond). Published 16 September 2023. doi:10.
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