Puberty in boys with type 1 diabetes mellitus: What has changed?
Authors' conclusion
A considerable number of Greek boys with T1DM appear to develop precocious and early puberty, raising thoughts regarding diabetes management and other possible cofactors.
Study context
- Population
- Boys with T1D with documented pubertal onset after T1D diagnosis, followed at 2 centres in North Greece (Aristotle University of Thessaloniki), March–June 2022
- Participants
- 46 participants
- Outcome
- Age of pubertal onset (testis volume >3 ml)
Methodological detailstwo-centre
- Two-centre
Main finding
As reported in the abstract
Timing of pubertal onset
Precocious puberty (<9 years old)
5 boys
10.2 %
Early puberty (<10 years but >9 years)
10
20.4 %
Normal pubertal onset
34
69.4 %
Observational data: associations, not effects.
Further findings
T1D duration and earlier puberty
- T1D duration inversely correlated with likelihood of earlier puberty
- P < 0.001
Secular trend
- No notable year predominance, suggesting no COVID-19 effect
Original publication
Puberty in boys with type 1 diabetes mellitus: What has changed? Diabetes Res Clin Pract. Published 20 July 2023. doi:10. 1016/ j. diabres. 2023. 110837
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