Type 1 diabetes

Puberty in boys with type 1 diabetes mellitus: What has changed?

Diabetes Res Clin PractPublished Cross-sectional study

Authors' conclusion

A considerable number of Greek boys with T1DM appear to develop precocious and early puberty, raising thoughts regarding diabetes management and other possible cofactors.

Study context

Population
Boys with T1D with documented pubertal onset after T1D diagnosis, followed at 2 centres in North Greece (Aristotle University of Thessaloniki), March–June 2022
Participants
46 participants
Outcome
Age of pubertal onset (testis volume >3 ml)
Methodological detailstwo-centre
  • Two-centre

Main finding

As reported in the abstract

Timing of pubertal onset

Precocious puberty (<9 years old)

5 boys

10.2 %

Early puberty (<10 years but >9 years)

10

20.4 %

Normal pubertal onset

34

69.4 %

Observational data: associations, not effects.

Further findings

T1D duration and earlier puberty

T1D duration inversely correlated with likelihood of earlier puberty
P < 0.001

Secular trend

No notable year predominance, suggesting no COVID-19 effect

Original publication

Puberty in boys with type 1 diabetes mellitus: What has changed? Diabetes Res Clin Pract. Published 20 July 2023. doi:10.1016/j.diabres.2023.110837

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