Protein intake and bone health: an umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society
Authors' conclusion
Since protein intakes in low/control and high/intervention groups were very heterogeneous and with low certainty of evidence, it remains unclear whether a dose above the current recommendation or type of protein intake (animal or plant protein) affects bone health overall. However, there is possible evidence for reduced hip fracture risk with high versus low protein intake.
Study context
- Population
- Younger and older adults; Systematic reviews (SRs) of randomized controlled trials (RCTs) and/or cohort studiesSRs of RCTs and/or cohort studies
- Participants
- 11 participants
- Comparison
- Protein intake above the current recommendation (high/intervention) vs low/control intake; animal or plant protein
- Outcome
- BMD and fracture risk
Methodological detailssystematic literature search (PubMed, Embase, Cochrane Database of Systematic Reviews), SRs of prospective studies published 11/2008–08/2021, methodological quality and certainty of evidence assessed with established tools and predefined criteria, for the evidence-based guideline of the German Nutrition Society
- Systematic literature search (PubMed, Embase, Cochrane Database of Systematic Reviews)
- SRs of prospective studies published 11/2008–08/2021
- Methodological quality and certainty of evidence assessed with established tools and predefined criteria
- For the evidence-based guideline of the German Nutrition Society
Recommendations
As reported in the abstract
Overall certainty of evidence for total, animal or plant protein intake on each outcome
- Overall certainty of evidence rated "insufficient" for each investigated outcome
- Exception: possible evidence for a reduced hip fracture risk by high vs low protein intake
- Vast majority of outcome-specific certainty of evidence rated "low" or "very low"
Original publication
Protein intake and bone health: an umbrella review of systematic reviews for the evidence-based guideline of the German Nutrition Society. Osteoporos Int. Published 1 May 2023. doi:10.
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