Prospective Associations of Maternal Cardiometabolic Health With Children Cardiometabolic Health at Ages 3 to 6 Years
Authors' conclusion
Better MCMH in pregnancy was associated with better CCMH at ages 3∼6 years.
Study context
- Population
- Mother-child dyads, Shanghai Maternal-Child Pairs Cohort; Maternal cardiometabolic health (MCMH) assessed at mean 27.8 (24–36) weeks' gestation by Life Essential 8; Children CMH (CCMH) at age 3 to 6 by 5 metrics
- Participants
- 1,478 mother-child dyads
- Exposure
- Maternal cardiometabolic health (MCMH) score in pregnancy and child cardiometabolic health (CCMH) at 3–6 years
- Outcome
- CCMH score (BMI, physical activity, sleep health, diet quality, nicotine exposure)
- Follow-up
- Ages 3 to 6 years
Main finding
As reported in the abstract
CCMH score per 10-point increase in MCMH score
Mean (SD) MCMH score during pregnancy
67.07
SD 8.82
Mean (SD) CCMH score
73.80
SD 10.75
β for CCMH score per 10-point higher MCMH score, adjusted (95% CI .22, 1.47)
.85
Observational data: associations, not effects.
Further findings
Subgroups by sex
- Similar results in girls but not in boys
Child overweight/obesity with increased MCMH score
- RR (95% CI .96, .99)
- .98
Child hypertension with increased MCMH score
- RR (95% CI .47, .92)
- .66
Sensitivity analysis: CCMH by 6 metrics (adding blood pressure), 499 children
- Similar results
Original publication
Prospective Associations of Maternal Cardiometabolic Health With Children Cardiometabolic Health at Ages 3 to 6 Years. J Clin Endocrinol Metab. Published 13 June 2024. doi:10. 1210/ clinem/ dgae413
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