Obesity

Predictors of racial differences in weight loss: the PROPEL trial

Obesity (Silver Spring)Published Secondary analysis of the PROPEL cluster-randomised trial

An erratum to this article was published (Obesity (Silver Spring), Jun 2024 ↗)

Authors' conclusion

Strategies specifically targeting engagement, such as improving session attendance and self-weighing behaviors, among African American individuals are needed to support more equitable weight losses over extended time periods.

Study context

Population
Patients in the intervention arm of the PROPEL trial, primary care clinics in Louisianaintervention arm
Participants
445 patients
Comparison
African American vs other racial groups
Primary endpoint
Mediation of the race–weight loss relationship by treatment engagement, psychosocial and lifestyle factors
Methodological detailscounterfactual mediation analysis, cluster-randomized, two-arm, primary care clinics
  • Counterfactual mediation analysis
  • Cluster-randomized
  • Two-arm
  • Primary care clinics

Primary result

As reported in the abstract

Proportion of racial differences in weight loss mediated

Daily weighing mediated, at 6 months (p = 0.008)

33%

Session attendance mediated, at 24 months (p = 0.027)

35%

Daily weighing mediated, at 24 months (p = 0.005)

66%

Original publication

Predictors of racial differences in weight loss: the PROPEL trial. Obesity (Silver Spring). Published 6 December 2023. doi:10.1002/oby.23936

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