Prolonged latency of the gustatory evoked potentials for sucrose solution in subjects living with obesity compared with normal-weight subjects
Authors' conclusion
This study highlights a slower activation in the taste cortex in OB compared with NW.
Study context
- Population
- Subjects living with obesity matched to normal-weight subjects; Gustatory evoked potentials (GEP) for sucrose solution (10 g.100 mL-1) recorded before and after a standard lunch low in sugar or no lunchmatched
- Participants
- 28 vs 22
- Comparison
- Subjects living with obesity vs normal-weight subjects
- Obesity (OB)n = 28
- NWn = 22reference
- Outcome
- Characteristics of gustatory evoked potentials (GEP) for sucrose solution (10 g.100 mL-1)
- Follow-up
- Before and after a standard lunch
Methodological detailsmatched, randomized session order (fasting vs feeding sessions, 2 days apart)
- Matched
- Randomized session order (fasting vs feeding sessions, 2 days apart)
Main finding
As reported in the abstract
GEP latency in Cz · morning
P < 0.001
Observational data: associations, not effects.
Secondary outcomes
Correlations of GEP latency (P1Cz) with plasma ghrelin, leptin, insulin (all participants)
- Ghrelin, r
- −0.38
- Leptin, r
- 0.33
- Insulin, r
- 0.37
- p < 0.0001
Original publication
Prolonged latency of the gustatory evoked potentials for sucrose solution in subjects living with obesity compared with normal-weight subjects. Int J Obes (Lond). Published 25 August 2024. doi:10.
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