Gestational diabetes & diabetes in pregnancy
Progression from gestational diabetes to type 2 diabetes mellitus: A prospective observational study from a resource constrained country-Pakistan
Authors' conclusion
A 43.1 % of the women progressed to T2DM during the study period.
Study context
- Population
- Women diagnosed with gestational diabetes mellitus (GDM) by OGTT, followed up for at least 03 years; Baqai Institute of Diabetology and Endocrinology (BIDE), Baqai Medical University (BMU) and Dow University of Health Sciences (DUHS), Pakistan, July 2019- September 2023; mean age 33.2 ± 7.2 years, mean BMI 31.3 ± 6.1 kg/m²
- Participants
- 489 women
- Outcome
- Progression to T2DM after GDM diagnosis
- Follow-up
- After delivery, at six months, at one year, at two and three years
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Progression to T2DM · during the study period
Women progressed to T2DM
43.1 %
Observational data: associations, not effects.
Further findings
Timing of progression among those who developed T2DM · within 1 year after GDM diagnosis
- Developed T2DM within 1 year after GDM diagnosis
- 53.8 %
Factors associated with T2DM risk
- Hypertension, urinary tract infections and jaundice significantly increased the risk
- Insulin treatment during pregnancy reduced the odds of T2DM; advancing age and pregnancy complications increased the risk
Original publication
Progression from gestational diabetes to type 2 diabetes mellitus: A prospective observational study from a resource constrained country-Pakistan. Diabetes Res Clin Pract. Published 2 May 2025. doi:10. 1016/ j. diabres. 2025. 112206
Composed by AI from the published abstract and checked against it. How Briefs are made →