Prevalence and risk factors for impaired awareness of hypoglycaemia: A registry‐based study of 10,202 adults with type 1 diabetes in Norway
Authors' conclusion
In this nationwide study, the IAH prevalence was 18.0%. Multiple hypoglycaemic events, female sex and diabetes duration were identified as important risk factors for IAH. Study findings highlight the complexity of self-reported hypoglycaemia symptom awareness and emphasise the importance of routinely addressing symptom awareness in diabetes follow-up.
Study context
- Population
- Adults (≥18 years) with T1D in the Norwegian Diabetes Register for Adults; hypoglycaemia awareness by 1-item Gold scale
- Participants
- 10,202 adults
- Outcome
- Prevalence of impaired awareness of hypoglycaemia (IAH; Gold score ≥4)
Methodological detailsnationwide, Norwegian Diabetes Register for Adults
- Nationwide
- Norwegian Diabetes Register for Adults
Main finding
As reported in the abstract
IAH prevalence
Overall impaired awareness of hypoglycaemia (IAH) prevalence
18.0%
95% CI 17.2, 18.7
Observational data: associations, not effects.
Further findings
IAH by age, diabetes duration and HbA1c (continuous)
- Prevalence increased linearly with age
- Diabetes duration and HbA1c: non-linear associations, higher prevalence in both lower and higher tails
Risk factors for IAH (log-binomial regression)
- Higher risk: multiple severe hypoglycaemic events, female sex, age ≥ 65 years, diabetes duration ≤4 years or ≥ 30 years, multiple DKA events, CGM use
- Lower risk: HbA1c 65-74 mmol/mol (8.1-8.9%)
Original publication
Prevalence and risk factors for impaired awareness of hypoglycaemia: A registry‐based study of 10,202 adults with type 1 diabetes in Norway. Diabet Med. Published 15 November 2024. doi:10.
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