Type 2 & other diabetes

Prevalence of youth type 2 diabetes in global Indigenous populations: a systematic review

DiabetologiaPublished Systematic review

Authors' conclusion

Youth type 2 diabetes prevalence in Indigenous populations is very high, particularly in young adulthood, and among the female sex. Prevalence has increased over time. Future research should stratify data by age and pubertal status, and identify both protective and risk factors to inform targeted prevention strategies. Indigenous-led, community-specific approaches that actively engage youth are critical in the development and implementation of diabetes surveillance, prevention and management programmes.

Study context

Population
Indigenous youth aged <25 years, all regions; cross-sectional observational studies, 1980–202449 studies
Outcome
T2D point prevalence (per 1000) and prevalence trends
Methodological detailsno meta-analysis (heterogeneity), modified Newcastle-Ottawa Scale quality assessment
  • No meta-analysis (heterogeneity)
  • Modified Newcastle-Ottawa Scale quality assessment

Pooled result

As reported in the abstract

Total T2D prevalence

Total T2D prevalence (33 of 49 studies, 36 populations, six countries and two self-governing states)

0-44 per 1000

Populations reporting prevalence >1 per 1000

75%

27/36

Further pooled results

Age-specific T2D prevalence (44 studies)

Age <10 years
0-4 per 1000
Age 10-19 years
0-44 per 1000
Age 15-25 years
0-64 per 1000
  • Increased prevalence with age

Gender-specific T2D prevalence (22 studies)

Studies showing female predominance
77%

Secular trends (12 studies since 1981)

Rising prevalence in young adults (15-25 years)
eight of ten studies
Rising prevalence in youth <15 years
six of nine studies

Original publication

Prevalence of youth type 2 diabetes in global Indigenous populations: a systematic review. Diabetologia. Published 2 October 2025. doi:10.1007/s00125-025-06556-7

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