Glycemic Level Modifies the Relationship Between Maternal Gestational Weight Gain and Neonatal Birth Weight in Type 2 Diabetes–Complicated Pregnancies
Authors' conclusion
Overly stringent weight control should be treated with caution if optimal glycemic control is not achieved.
Study context
- Population
- Pregnant women with T2D, stratified by third-trimester glycemic control
- Participants
- 1,642 women
- Exposure
- Excessive vs adequate gestational weight gain (GWG), by third-trimester glycaemic control
- Outcome
- Effect of eGWG vs adequate GWG by glycemic control stratum
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Birth weight increase with eGWG: suboptimal vs optimal glycemic control
361.04 vs. 126.07 g
P = 0.007
aOR for macrosomia with eGWG: suboptimal vs optimal glycemic control
4.26 vs. 2.73
P = 0.002
Cesarean delivery (effect estimate) with eGWG: suboptimal vs optimal glycemic control
1.86 vs. 1.52
P = 0.738
Observational data: associations, not effects.
Original publication
Glycemic Level Modifies the Relationship Between Maternal Gestational Weight Gain and Neonatal Birth Weight in Type 2 Diabetes–Complicated Pregnancies. Diabetes Care. Published 1 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →