Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c
Authors' conclusion
In these regions, the use of FPG alone may delay diabetes diagnosis and underestimate diabetes prevalence.
Study context
- Population
- Population-based studies in different world regions; people with previously undiagnosed diabetes detected in survey screening by fasting plasma glucose (FPG) and/or hemoglobin A1c (HbA1c)117 population-based studies
- Outcome
- Age-standardized proportion of diabetes previously undiagnosed and detected in survey screening
Methodological detailsage-standardized, prediction equations, Prediction equations developed for probability of elevated HbA1c at a given FPG level in people without diagnosed diabetes, and vice versa
- Age-standardized
- Prediction equations
- Prediction equations developed for probability of elevated HbA1c at a given FPG level in people without diagnosed diabetes, and vice versa
Pooled result
As reported in the abstract
High-income western region
30%
South Asia
66%
Further pooled results
Screen-detected diabetes (either test) with elevated both FPG and HbA1c, age-standardized
- Range across regions; remainder had discordant elevation of FPG or HbA1c
- 29-39%
Isolated elevated HbA1c vs isolated elevated FPG
- In most low- and middle-income regions, isolated elevated HbA1c more common than isolated elevated FPG
Original publication
Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c. Nat Med. Published 9 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →