Prevalence and risk factors for osteoporosis in type 1 diabetes—results from an observational study
Authors' conclusion
The present study finds that a high proportion of individuals with type 1 diabetes have osteoporosis, and an even higher proportion meet the treatment criteria proposed by the ADA
Study context
- Population
- Active attenders of the T1D clinic at Steno Diabetes Center Aarhus, Aarhus University Hospital, offered osteoporosis screening by DXA of lumbar spine and hip, 2020–2022had a DXA
- Participants
- 764 participants
- Outcome
- Prevalence of osteoporosis (WHO criteria: vertebral fracture or T-score ≤ - 2.5) and of ADA-treatment criteria (vertebral fracture or T-score ≤ - 2.0)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Osteoporosis (vertebral fracture or T-score ≤ - 2.5)
25.5%
Met ADA-treatment criteria (vertebral fracture or T-score ≤ - 2.0)
36%
Observational data: associations, not effects.
Further findings
Risk factors for osteoporosis (multivariate analysis)
| OR (95% CI) | ||
|---|---|---|
| Increasing ageIncreased risk · multivariate analysis | 1.3 (1.0–1.7) | |
| Family history of osteoporosisIncreased risk · multivariate analysis | 1.9 (1.2–3.0) | |
| Increase in BMIDecreased risk · multivariate analysis | 0.87 (0.82–0.92) | |
| 0.20.5125Odds ratio (log scale) |
Original publication
Prevalence and risk factors for osteoporosis in type 1 diabetes—results from an observational study. Osteoporos Int. Published 18 March 2025. doi:10.
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