Type 2 & other diabetes

Prevalence and incidence of mild cognitive impairment in adults with diabetes in the United States

Diabetes Res Clin PractPublished Secondary analysis of the Health and Retirement Study

Primary result · Prevalence of MCIResult — go to the resultOdds ratio 1.468 95 % CI 1.337–1.611

Authors' conclusion

Using a nationally representative study data in the U.S., participants with diabetes had a higher prevalence and incidence of MCI than those without diabetes. Findings show the importance of developing interventions tailored to the needs of individuals with diabetes and cognitive impairment.

Study context

Population
US adults in the Health and Retirement Study (1996–2018); prevalence sample 14,988 (4192 [28.0%] with diabetes), incidence sample 21,824 (1534 [28.0%] with diabetes)prevalence 14,988
Comparison
Diabetes vs no diabetes
Primary endpoint
Prevalence and incidence of mild cognitive impairment (MCI)
Methodological detailsHealth and Retirement Study (HRS), nationally representative
  • HRS
  • Nationally representative

Primary result

Prevalence of MCI

Odds ratio

1.468

95 % CI 1.337–1.611

P < 0.001

By group

Diabetesvs Non-diabetes
OR 1.468 (95 % CI 1.337–1.611); P < 0.001

As reported in the abstract

Further findings

%

OutcomeDiabetesNon-diabetesEstimateP value
Incidence of MCI (newly diagnosed diabetes vs none) · mean 10-year follow-up42.931.6IRR 1.314 (95 % CI 1.213–1.424)P < 0.001
Incidence of MCI (newly diagnosed diabetes vs none) · mean 10-year follow-upuncontrolled HR 1.498 (95 % CI 1.405–1.597)P < 0.001

Original publication

Prevalence and incidence of mild cognitive impairment in adults with diabetes in the United States. Diabetes Res Clin Pract. Published 25 October 2023. doi:10.1016/j.diabres.2023.110976

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