Preoperative Fine-Needle Aspiration in Goiter With Compressive Symptoms: A Systematic Review and Meta-analysis
Pooled result · FNA accuracy vs final histologyResult — go to the resultRelative risk 0.79Authors' conclusion
Our data underscore the significant value of preoperative FNA when planning a thyroidectomy for patients with a goiter. The FNA results enable both the physician and the patient to make informed decisions, consider a staged surgical approach if necessary, determine an appropriate follow-up strategy, and discuss potential complications based on the preoperative findings.
Study context
- Population
- Adults with euthyroid goiter and compressive symptoms designated to undergo therapeutic surgery14 studies
- Comparison
- Preoperative fine-needle aspiration (FNA) vs final histology
- Outcome
- Final histology compared with preoperative FNA
Methodological detailsPRISMA guidelines, risk of bias assessed with risk of bias visualization (ROBVIS), 3304 studies identified at initial search, Two reviewers independently extracted data
- PRISMA guidelines
- Risk of bias assessed with ROBVIS
- 3304 studies identified at initial search
- Two reviewers independently extracted data
Pooled result
FNA accuracy vs final histology
Relative risk
0.79
By group
Preoperative FNA
88.4%
As reported in the abstract
Original publication
Preoperative Fine-Needle Aspiration in Goiter With Compressive Symptoms: A Systematic Review and Meta-analysis. Endocr Pract. Published 12 May 2025. doi:10.
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