Gestational diabetes & diabetes in pregnancy

Pregestational and gestational diabetes mellitus and risk of postpartum kidney disease: A retrospective cohort study

Diabetes Res Clin PractPublished Retrospective cohort study

Authors' conclusion

The substantially increased risk of postpartum readmission for kidney disease associated with PGDM and, to a lesser extent, with GDM underscores the need for improved surveillance for kidney complications in women with PGDM and GDM.

Study context

Population
Women aged 15–54 with deliveries, Nationwide Readmissions Database 2010–2020; prior hospitalization for any kidney disease before delivery excluded
Exposure
PGDM or Gestational Diabetes Mellitus (GDM) vs no diabetes
Outcome
Readmission for kidney disease (Acute Kidney Injury (AKI), Chronic Kidney Disease (CKD))
Follow-up
Same calendar year of delivery
Methodological detailsnationwide database (Nationwide Readmissions Database 2010-2020), Cox regression
  • Nationwide database (Nationwide Readmissions Database 2010-2020)
  • Cox regression

Main finding

As reported in the abstract

Each group vs without diabetesAdjusted hazard ratio (95% CI)
PGDMAKI
9.07(8.44–9.75)
PGDMCKD
20.73(18.00–23.87)
GDMAKI
1.25(1.16–1.35)
GDMCKD
1.34(1.14–1.58)

Observational data: associations, not effects.

Original publication

Pregestational and gestational diabetes mellitus and risk of postpartum kidney disease: A retrospective cohort study. Diabetes Res Clin Pract. Published 16 June 2025. doi:10.1016/j.diabres.2025.112330

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