Lipids & metabolic liver disease
The predictive value of atherogenic index of plasma for cardiovascular outcomes in patients with acute coronary syndrome undergoing percutaneous coronary intervention with low-density lipoprotein-cholesterol (LDL-C) below 1.8mmol/L
Authors' conclusion
The present study demonstrates that AIP is a significant predictor of adverse outcomes in ACS patients undergoing PCI with LDL-C < 1.8mmol/L. These results suggest that AIP may offer supplementary prognostic information for ACS patients with optimally managed LDL-C levels.
Study context
- Population
- Patients with acute coronary syndrome (ACS) and LDL-C below 1.8mmol/L who underwent percutaneous coronary intervention (PCI)
- Participants
- 1,133 patients
- Exposure
- High atherogenic index of plasma (AIP) vs low AIP
- Outcome
- MACCE: composite of all-cause death, nonfatal MI, ischemic stroke or unplanned repeat revascularization
- Follow-up
- Median 26 months
Main finding
As reported in the abstract
MACCE
Hazard ratio (95% CI)
Between High AIP and Low AIPmultivariable-adjusted; AIP as nominal variable
1.62(1.04–2.53)
AIP (continuous)multivariable-adjusted; AIP as continuous variable
2.01(1.09–3.73)
Observational data: associations, not effects.
Further findings
Unplanned repeat revascularization · median follow-up 26 months · MACCE difference mainly derived from this component
P log-rank = 0.028
Original publication
The predictive value of atherogenic index of plasma for cardiovascular outcomes in patients with acute coronary syndrome undergoing percutaneous coronary intervention with LDL-C below 1.8mmol/L. Cardiovasc Diabetol. Published 26 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →