Pre-pregnancy body mass index and adverse maternal and perinatal outcomes in twins: A population retrospective cohort study
Main finding · SMM (rate per 10,000 pregnancies) and composite perinatal outcome (death and severe morbidity)Result — go to the resultAdjusted relative risk 1.79 95% CI 1.32–2.43Authors' conclusion
There was no evidence of elevated risk of adverse outcomes among twin pregnancies of women who were overweight or obese. Risk was higher in underweight women, who may require specific care when carrying twins.
Study context
- Population
- All twin births at ≥ 20 weeks gestation in British Columbia, Canada, 2000–2017women with twin pregnancy
- Participants
- 7,770 births
- Exposure
- Pre-pregnancy BMI categories
- Underweightn = 368
- Overweightn = 1,704
- Obesen = 1,016
- Outcome
- Primary outcomes: Severe maternal morbidity (SMM) and composite perinatal outcome (perinatal death and severe neonatal morbidity)
Methodological detailsconfounder-adjusted robust Poisson regression
- Confounder-adjusted robust Poisson regression
Main finding
As reported in the abstract
SMM (rate per 10,000 pregnancies) and composite perinatal outcome (death and severe morbidity)
Adjusted relative risk
1.79
95% CI 1.32–2.43
By group
Underweight
aRR 1.79 (95% CI 1.32–2.43)
Per 10,000 pregnancies, as printed
- Little association between obesity and any primary outcome; composite perinatal outcome aRR
- 1.09 (0.85, 1.38) (95% CI)
Observational data: associations, not effects.
Original publication
Pre-pregnancy body mass index and adverse maternal and perinatal outcomes in twins: A population retrospective cohort study. Int J Obes (Lond). Published 18 May 2023. doi:10.
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