Type 1 diabetes

Pre‐exercise protein intake is associated with reduced time in hypoglycaemia among adolescents with type 1 diabetes

Diabetes Obes MetabPublished Secondary analysis of a randomised trial

Authors' conclusion

Among adolescents with T1D, a dose of ≥10 g or ≥0.125 g/kg of protein within 4 h before MVPA may promote reduced time in hypoglycaemia during, but not following, physical activity.

Study context

Population
Adolescents with T1D, 14.5 (13.8, 15.7) years, 36.6% overweight/obese, in a randomized trial of an adaptive behavioural intervention
Participants
112 adolescents
Comparison
Pre-exercise protein intake vs no protein
Primary endpoint
CGM time below range (TBR) (<70 mg/dl) during MVPA bouts
Methodological detailsmixed effects regression models
  • Mixed effects regression models

Primary result

As reported in the abstract

TBR during physical activity
10-19.9 g
absolute reduction −4.41 %; P = 0.04
>20 g
absolute reduction −4.83 %; P = 0.02
0.125-0.249 g/kg
absolute reduction −5.38 %; P = 0.01
≥0.25 g/kg
absolute reduction −4.32 %; P = 0.03

Further findings

No significant association between protein intake and measures of glycaemia following bouts of moderate-to-vigorous physical activity (MVPA)

Original publication

Pre‐exercise protein intake is associated with reduced time in hypoglycaemia among adolescents with type 1 diabetes. Diabetes Obes Metab. Published 15 January 2024. doi:10.1111/dom.15438

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