Potassium Iodide Use and Patient Outcomes for Thyroid Storm: An Observational Study
Main finding · In-hospital mortalityResult — go to the resultOdds ratio 0.91 95% CI 0.62–1.34Authors' conclusion
Our findings suggest that KI may reduce in-hospital mortality among patients hospitalized for thyroid storm with Graves' disease.
Study context
- Population
- Patients hospitalized with thyroid storm, Japanese Diagnosis Procedure Combination database, July 2010–March 2022
- Participants
- 3,188 eligible patients
- Exposure
- KI within 2 days of admission vs no KI
- KIn = 2,350
- non-KIn = 838reference
- Outcome
- In-hospital mortality
Methodological detailsobservational, nationwide inpatient database, prespecified subgroup analyses by Graves' disease diagnosis
- Observational
- Nationwide inpatient database
- Prespecified subgroup analyses by Graves' disease diagnosis
Main finding
As reported in the abstract
Odds ratio
0.91
95% CI 0.62–1.34
Events by group
KIvs non-KI
OR 0.91 (95% CI 0.62–1.34)
Observational data: associations, not effects.
Further findings
| Outcome | Estimate | |
|---|---|---|
| In-hospital mortality, patients with GD diagnosisPrespecified subgroup analysis | OR 0.46 (95% CI 0.25–0.88) | |
| In-hospital mortality, patients without GD diagnosisPrespecified subgroup analysis | OR 1.11 (95% CI 0.67–1.85) | |
| LOSShorter with KI | subdistribution HR 1.15 (95% CI 1.05–1.27) | |
| Total hospitalization costs | OR 0.92 (95% CI 0.85–1.00) | |
| 0.20.5125Ratio (log scale) |
Original publication
Potassium Iodide Use and Patient Outcomes for Thyroid Storm: An Observational Study. J Clin Endocrinol Metab. Published 28 March 2024. doi:10.
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