Reproductive endocrinology

Polycystic ovary syndrome is associated with weight‐loss attempts and perception of overweight independent of BMI: a population‐based cohort study

Obesity (Silver Spring)Published Population-based birth cohort study

Authors' conclusion

Women with PCOS were more likely to have experienced multiple weight-loss attempts and a perception of having overweight compared with control individuals, regardless of obesity status.

Study context

Population
Women with and without polycystic ovary syndrome (PCOS) from a population-based birth cohort, examined at ages 31 and 46 years
Participants
278 vs 1,560
Exposure
Women with PCOS vs without PCOS
  • PCOSn = 278
  • Controln = 1,560reference
Outcome
Weight-loss attempts, regardless of BMI
Follow-up
Ages 31 and 46 years
Methodological detailsquestionnaires and clinical examinations at ages 31 and 46 years
  • Questionnaires and clinical examinations at ages 31 and 46 years

Main finding

As reported in the abstract

Weight-loss attempts · age 31 years

P < 0.001

Observational data: associations, not effects.

Further findings

Weight-loss attempts · age 46 years

P < 0.001

Perception of having overweight, among participants with normal weight · age 31 years

P = 0.014

Perception of having overweight, among participants with normal weight · age 46 years

P = 0.001

OutcomeOR (95% CI)P value
Multiple weight-loss attempts · age 46 yearsAdjusted model1.43 (1.00–2.03)P = 0.05

Original publication

Polycystic ovary syndrome is associated with weight‐loss attempts and perception of overweight independent of BMI: a population‐based cohort study. Obesity (Silver Spring). Published 28 February 2023. doi:10.1002/oby.23681

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