Childhood sleep behaviors and polycystic ovary syndrome risk in adolescence: the Raine study cohort longitudinal study
Main finding · Sleep behavior problem scores, childhood to adolescenceResult — go to the resultAdjusted mean difference 0.49 95% CI 0.10–0.87Authors' conclusion
Sleep difficulties may serve as early, modifiable behavioral markers of PCOS risk.
Study context
- Population
- Female participants of the Raine Study cohort; sleep behaviors (Child Behavior Checklist) at ages 5, 8, 10 and 14 years37 with polycystic ovary syndrome (PCOS)
- Participants
- 226 participants
- Exposure
- PCOS vs no PCOS at age 14 years
- PCOSn = 37
- Outcome
- Longitudinal sleep behavior problem scores by PCOS status
- Follow-up
- Ages 5 to 14 years
Methodological detailslongitudinal, Raine Study cohort
- Longitudinal
- Raine Study cohort
Main finding
As reported in the abstract
Sleep behavior problem scores, childhood to adolescence
Adjusted mean difference
0.49
95% CI 0.10–0.87
P = 0.013
PCOSvs No PCOS
adjusted mean difference 0.49 (95% CI 0.10–0.87); P = 0.013
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| "Trouble sleeping" at age 10 and PCOS at age 14 | 2.95 (1.30–6.69) | |
| "Sleeping less than most kids" at age 10 and PCOS at age 14 | 2.48 (1.18–5.22) | |
| 0.10.31310Odds ratio (log scale) |
Original publication
Childhood sleep behaviors and polycystic ovary syndrome risk in adolescence: the Raine study cohort longitudinal study. J Clin Endocrinol Metab. Published 25 February 2026. doi:10.
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