Plant-Based Dietary Patterns Associated With Reduced Risk of All-Cause Mortality in Diabetes Subgroups: A Prospective Cohort Study From the UK Biobank
Authors' conclusion
Higher PDI adherence was associated with decreased mortality risk and higher unhealthy PDI adherence with an increased mortality risk. There was an indication for differences in these association depending on diabetes subgroups.
Study context
- Population
- UK Biobank participants with T2D and at least two 24-h dietary recalls679 deaths
- Participants
- 4,829 participants
- Exposure
- Highest (T3) vs lowest (T1) tertile of adherence to PDI, healthy PDI and unhealthy PDI
- Outcome
- All-cause mortality
- Follow-up
- Mean 11.3 years
Methodological detailsUK Biobank, multivariable Cox regression
- UK Biobank
- Multivariable Cox regression
Main finding
As reported in the abstract
T3 vs T1Hazard ratio (95% CI)
PDI
0.79(0.63–0.99)
Healthy PDI; 95% CI included the null value
0.82(0.67–1.02)
Unhealthy PDI
1.24(1.00–1.54)
Observational data: associations, not effects.
Further findings
Interaction with diabetes subgroups (HbA1c, waist circumference, age at diagnosis, diabetes duration)
- Associations of PDI, healthy PDI and unhealthy PDI with mortality more pronounced with poorer glycaemic control, higher waist circumference, earlier diagnosis and longer diabetes duration
Original publication
Plant-Based Dietary Patterns Associated With Reduced Risk of All-Cause Mortality in Diabetes Subgroups: A Prospective Cohort Study From the UK Biobank. Diabetes Care. Published 28 August 2025. doi:10.
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