Physical activity and sedentary time across pregnancy and associations with neonatal weight, adiposity and cord blood parameters: a secondary analysis of the DALI study
Authors' conclusion
Maternal MVPA is associated with neonatal fat mass, but not birthweight, in male offspring. Our findings underline the importance of physical activity throughout pregnancy.
Study context
- Population
- Pregnant women with BMI ≥ 29 kg/m² in the DALI study and their offspring
- Participants
- 213 mother-child pairs
- Comparison
- Maternal moderate-to-vigorous PA (MVPA) and sedentary time across pregnancy
- Primary endpoint
- Birthweight, neonatal adiposity (FM%) and cord blood parameters (C-peptide, leptin, lipids)
Methodological detailscohort analysis, Bayesian multilevel models, accelerometer-measured, interactions with offspring sex
- Cohort analysis
- Bayesian multilevel models
- Accelerometer-measured
- Interactions with offspring sex
Primary result
As reported in the abstract
Higher maternal mean MVPA and offspring fat mass (FM)%, males
−0.520%
95% CI −1.011%, −0.031%
Increasing MVPA and offspring FM%, males
−4.649%
CI −7.876%, −1.432%
Mean sedentary time (ST) and cord blood C-peptide, females
−0.145 µg/l
CI −0.279 µg/l, −0.005 µg/l
Further findings
Change in MVPA and ST across gestation
- Almost all women decreased MVPA and increased ST throughout gestation
Original publication
Physical activity and sedentary time across pregnancy and associations with neonatal weight, adiposity and cord blood parameters: a secondary analysis of the DALI study. Int J Obes (Lond). Published 27 July 2023. doi:10.
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