Obesity

Physical activity and weight loss in a pragmatic weight loss trial

Int J Obes (Lond)Published Secondary analysis of a cluster-randomised weight loss trial

Authors' conclusion

In conclusion, this multi-component intervention resulted in clinically significant weight loss, and greater increases in physical activity over the intervention period were associated with greater percent reductions in body weight.

Study context

Population
Underserved population in Louisiana; intervention group of a 24-month multi-component weight loss program delivered by health coaches in primary care clinics
Participants
402 participants
Comparison
Tertiles of change in physical activity, baseline to 24 months
  • Interventionn = 402
Primary endpoint
Percent weight change from baseline by change in physical activity
Follow-up
24 months
Methodological detailspragmatic, cluster-randomized, intervention group only
  • Pragmatic
  • Cluster-randomized
  • Intervention group only

Primary result

As reported in the abstract

% weight change from baseline across increasing tertiles of change in walking · baseline to 24 months
% weight change (mean ± SE) across increasing tertiles of change in walking
−3.2 ± 1.0%, −5.5 ± 0.9%, and −7.3 ± 0.9%
P across tertiles
p = 0.001

Further findings

% weight change from baseline across increasing tertiles of change in moderate-to-vigorous-intensity activity · baseline to 24 months

% weight change (mean ± SE) across increasing tertiles of change in moderate-to-vigorous-intensity activity
−4.3 ± 1.0%, −5.0 ± 0.9%, and −7.0 ± 0.9%
P across tertiles
P = 0.04

Original publication

Physical activity and weight loss in a pragmatic weight loss trial. Int J Obes (Lond). Published 26 January 2023. doi:10.1038/s41366-023-01260-1

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