Obesity

Long‐term all‐cause and cause‐specific mortality for four bariatric surgery procedures

Obesity (Silver Spring)Published Retrospective matched cohort study

Main finding · All-cause mortalityResult — go to the resultHazard ratio 0.84 95% CI 0.79–0.90

Authors' conclusion

Reduced all-cause mortality was durable for multiple decades, for multiple bariatric surgical procedures, for females and males, and for greater than age 34 years at surgery. Rate of death from suicide was significantly higher in surgery versus non-surgery participants only in the youngest age at surgery participants.

Study context

Population
Participants with and without bariatric surgery, four procedures, multiple age-at-surgery groups21,837 matched pairs
Exposure
Bariatric surgery vs no surgery
Outcome
All-cause mortality
Follow-up
Up to 40 years (mean [SD], 13.2 [9.5] years)
Methodological detailsmatched 1:1 for age, sex, BMI and surgery date
  • Matched 1:1 for age, sex, BMI and surgery date

Main finding

As reported in the abstract

Hazard ratio

0.84

95% CI 0.79–0.90

P < 0.001

Surgeryvs Non-surgery
HR 0.84 (95% CI 0.79–0.90); P < 0.001

Observational data: associations, not effects.

Further findings

OutcomeHR (95% CI)P value
Suicide mortalityPrimarily in ages at surgery 18–34 years2.4 (1.57–3.68)P < 0.001

All-cause mortality by sex

Significantly lower mortality after surgery for both females and males

Cause-specific mortality (CVD, cancer, diabetes)

CVD mortality decrease, surgery vs non-surgery
29%
Cancer mortality decrease, surgery vs non-surgery
43%
Diabetes mortality decrease, surgery vs non-surgery
72%

Original publication

Long‐term all‐cause and cause‐specific mortality for four bariatric surgery procedures. Obesity (Silver Spring). Published 25 January 2023. doi:10.1002/oby.23646

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