Randomized controlled trial of a novel lifestyle intervention used with or without meal replacements in work sites
Authors' conclusion
A new lifestyle intervention approach, deliverable by videoconference with or without MR, supported clinically impactful weight loss in employees.
Study context
- Population
- Employees with overweight or obesity at 12 work sites; age 48 (SD 10) years, BMI 33 (6) kg/m², 83% female
- Participants
- 335 employees12 work sites
- Comparison
- HWL lifestyle intervention with or without meal replacements vs wait-listed control
- Primary endpoint
- Weight change
- Follow-up
- 6 months
Methodological detailscluster (work sites), wait-listed control, randomization within work sites to HWL or HWL + meal replacements (MR)
- Cluster (work sites)
- Wait-listed control
- Randomization within work sites to HWL or HWL + MR
Primary result
As reported in the abstract
HWL
−8.8%
mean · 95% CI −11.2%–-6.4%
HWL + MR
−8.0%
mean · 95% CI −10.4%–-5.5%
HWL vs Control: P < 0.001 · HWL + MR vs Control: P < 0.001 · HWL vs HWL + MR: P = 0.40
Secondary outcomes
- Clinically meaningful weight loss (≥5%) maintained at 18 months in both HWL and HWL + MR
- P < 0.001
Original publication
Randomized controlled trial of a novel lifestyle intervention used with or without meal replacements in work sites. Obesity (Silver Spring). Published 25 January 2023. doi:10.
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