Type 2 & other diabetes

Person‐Reported and Continuous Glucose Monitoring ( Continuous Glucose Monitor (CGM) ) Recorded Hypoglycaemia in People With Insulin‐Treated Type 2 Diabetes and Mild to Moderate Chronic Kidney Disease; Post Hoc Analysis From the Hypo‐ METRICS Study

Diabetes Obes MetabPublished Post hoc analysis of the Hypo-METRICS study

Authors' conclusion

In people with insulin-treated T2DM and CKD stages 2 or 3, the rates of SDH and PRH do not significantly differ from those in people without CKD.

Study context

Population
Insulin-treated T2D with > 1 hypoglycaemic episode within the last 3 months; blinded CGM and person-reported hypoglycaemia (PRH) recorded on app for 10 weeks
Participants
313 participants
Comparison
Chronic kidney disease (CKD) 1 vs CKD 2 vs CKD 3
  • CKD 1n = 117reference
  • CKD 2n = 140
  • CKD 3n = 56
Primary endpoint
Rates of sensor-detected (SDH) and person-reported hypoglycaemia (PRH)
Follow-up
10 weeks
Methodological detailsblinded CGM
  • Blinded CGM

Primary result

As reported in the abstract

SDH < 3.9 mmol/L, events per week

P = 0.12

Further findings

PRH events per week · 10 weeks · across CKD 1, CKD 2 and CKD 3

P = 0.24

OutcomeCKD 1CKD 2CKD 3P value
SDH <3.0 mmol/L, events per week · 10 weeksAcross CKD 1, CKD 2 and CKD 3median 0.20 (IQR 0.00–0.50) events per week— withheld: not confirmed against the abstract— withheld: not confirmed against the abstractP = 0.88

— withheld: the automatic checks could not confirm the value against the abstract

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Person‐Reported and Continuous Glucose Monitoring ( CGM ) Recorded Hypoglycaemia in People With Insulin‐Treated Type 2 Diabetes and Mild to Moderate Chronic Kidney Disease; Post Hoc Analysis From the Hypo‐ METRICS Study. Diabetes Obes Metab. Published 1 September 2026. doi:10.1111/dom.71247

Composed by AI from the published abstract and checked against it. How Briefs are made →

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