Person‐Reported and Continuous Glucose Monitoring ( Continuous Glucose Monitor (CGM) ) Recorded Hypoglycaemia in People With Insulin‐Treated Type 2 Diabetes and Mild to Moderate Chronic Kidney Disease; Post Hoc Analysis From the Hypo‐ METRICS Study
Authors' conclusion
In people with insulin-treated T2DM and CKD stages 2 or 3, the rates of SDH and PRH do not significantly differ from those in people without CKD.
Study context
- Population
- Insulin-treated T2D with > 1 hypoglycaemic episode within the last 3 months; blinded CGM and person-reported hypoglycaemia (PRH) recorded on app for 10 weeks
- Participants
- 313 participants
- Comparison
- Chronic kidney disease (CKD) 1 vs CKD 2 vs CKD 3
- CKD 1n = 117reference
- CKD 2n = 140
- CKD 3n = 56
- Primary endpoint
- Rates of sensor-detected (SDH) and person-reported hypoglycaemia (PRH)
- Follow-up
- 10 weeks
Methodological detailsblinded CGM
- Blinded CGM
Primary result
As reported in the abstract
SDH < 3.9 mmol/L, events per week
P = 0.12
Further findings
PRH events per week · 10 weeks · across CKD 1, CKD 2 and CKD 3
P = 0.24
| Outcome | CKD 1 | CKD 2 | CKD 3 | P value |
|---|---|---|---|---|
| SDH <3.0 mmol/L, events per week · 10 weeksAcross CKD 1, CKD 2 and CKD 3 | median 0.20 (IQR 0.00–0.50) events per week | — withheld: not confirmed against the abstract | — withheld: not confirmed against the abstract | P = 0.88 |
— withheld: the automatic checks could not confirm the value against the abstract
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Person‐Reported and Continuous Glucose Monitoring ( CGM ) Recorded Hypoglycaemia in People With Insulin‐Treated Type 2 Diabetes and Mild to Moderate Chronic Kidney Disease; Post Hoc Analysis From the Hypo‐ METRICS Study. Diabetes Obes Metab. Published 1 September 2026. doi:10. 1111/ dom. 71247
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