Associations Between Hypoglycemia Awareness Status and Symptoms of Hypoglycemia Among Adults with Type 1 or Insulin-Treated Type 2 Diabetes Using the Hypo-METRICS Smartphone Application
Authors' conclusion
The Hypo-METRICS app is sensitive to differences in hypoglycemia symptoms according to hypoglycemia awareness in both diabetes types.
Study context
- Population
- Adults with T1D or insulin-treated T2D with ≥1 hypoglycemic episode in previous 3 months; 48% T1D, 52% T2D, 45% women, 91% white, 59% used Flash or CGM
- Participants
- 531 adults
- Exposure
- Impaired awareness of hypoglycemia vs normal awareness, by Gold score
- Outcome
- Hypoglycemia symptoms (any of eight; present if rated "A little bit" to "Very much") reported in real time via the Hypo-METRICS app
- Follow-up
- 10 weeks
Methodological detailsreal-time symptom reporting via smartphone app, mixed-effects binary logistic regression adjusted for glucose monitoring method and diabetes duration
- Real-time symptom reporting via smartphone app
- Mixed-effects binary logistic regression adjusted for glucose monitoring method and diabetes duration
Main finding
As reported in the abstract
Reporting autonomic symptoms
IAH vs NAHOdds ratio (95% CI)P value
T1D
0.43(0.25–0.73)
P = 0.002T2D
0.51(0.26–0.99)
P = 0.048Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Autonomic symptoms at glucose <54vs >70 mg/dL, T1DHigher odds with IAH at <54 than >70 mg/dL | 2.18 (1.21–3.94) | P = 0.010 | |
| 0.20.5125Odds ratio (log scale) |
Original publication
Associations Between Hypoglycemia Awareness Status and Symptoms of Hypoglycemia Among Adults with Type 1 or Insulin-Treated Type 2 Diabetes Using the Hypo-METRICS Smartphone Application. Diabetes Technol Ther. Published 12 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →