Performance and interventional cutoffs of osteoporosis self-assessment tools in the community: implications for screening and early referral
Authors' conclusion
The cutoff of OSTAi is suitable for self-assessment of osteoporosis in Taiwanese women. However, for men, the cutoff of MOSTAi may need to be adjusted.
Study context
- Population
- Community subjects from epidemiological cohorts in Taiwan (52.8% women; mean age 65.4 years)
- Participants
- 1,976 subjects
- Comparison
- Osteoporosis self-assessment tools vs DXA-defined osteoporosis
- Outcome
- Sex- and age-specific sensitivity and specificity of self-assessment tools for predicting osteoporosis
Methodological detailscommunity-based, epidemiological cohorts
- Community-based
- Epidemiological cohorts
Performance
As reported in the abstract
Detection of osteoporosis
| Test or model | Sensitivity | Specificity |
|---|---|---|
| MOSTAi | 0.53 | 0.72 |
| OSTA | 0.71 | 0.77 |
| OSTAi | 0.77 | 0.73 |
Sensitivity
MOSTAi0.53
OSTA0.71
OSTAi0.77
Specificity
MOSTAi0.72
OSTA0.77
OSTAi0.73
Further findings
| Outcome | Values |
|---|---|
| eOSTAi in women: AUC | eOSTAi AUC for osteoporosis 0.8200 · AUC for osteopenia 0.7643 |
| eMOSTAi in men: AUC | eMOSTAi AUC for osteoporosis 0.6690 · AUC for osteopenia 0.5626 |
Cutoffs of eOSTAi and eMOSTAi for detecting osteoporosis
- Cutoffs decreased with age
Original publication
Performance and interventional cutoffs of osteoporosis self-assessment tools in the community: implications for screening and early referral. Osteoporos Int. Published 20 August 2025. doi:10.
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