Perceptions and Psychological Adverse Effects of Central Precocious Puberty or Early Normal Puberty, and Its Treatment Among Affected Girls and Their Caregivers
Authors' conclusion
This study demonstrated that girls and their caregivers lacked adequate knowledge of iCPP/ENP.
Study context
- Population
- Thai girls with idiopathic central precocious puberty or early normal puberty (iCPP/ENP) and their caregivers; mean (SD) age at enrolment 9.9 (1.1) years
- Participants
- 954 participants
- Exposure
- iCPP vs ENP vs Caregivers
- iCPPn = 340
- ENPn = 140
- Caregiversn = 474
- Outcome
- Perceptions and psychological adverse effects of iCPP/ENP
Methodological detailsquestionnaire-based
- Questionnaire-based
Main finding
As reported in the abstract
- Breast buds perceived as sign of puberty by girls
- 234 (49%)
- Body odour perceived as sign of puberty by girls
- 174 (36%)
- Acne perceived as sign of puberty by girls
- 162 (34%)
- Girls believing certain foods caused iCPP/ENP
- 216 (45%)
- Caregiver anxiety score on 10-point scale
- 8.3 (1.7)
Observational data: associations, not effects.
Further findings
Psychological effects in newly diagnosed girls (n=38)
- Reported being bullied (verbal harassment about breasts, breast grabbing)
- 8 (21%)
- Depression
- 4 (11%)
- Anxiety
- 9 (24%)
- Low self-esteem
- 5 (13%)
- Depression and anxiety more prevalent in iCPP group
Original publication
Perceptions and Psychological Adverse Effects of Central Precocious Puberty or Early Normal Puberty, and Its Treatment Among Affected Girls and Their Caregivers. Clin Endocrinol (Oxf). Published 7 May 2026. doi:10.
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