Type 1 diabetes

Participant and physician perspectives on the use of SGLT2 inhibitors in type 1 diabetes

Diabet MedPublished Qualitative descriptive study

Authors' conclusion

While there is great interest and motivation toward the use of SGLT2i among people with T1D and the physicians who treat them, there is also a clear understanding of the need for personalization of therapy and support for robust evidence to inform care.

Study context

Population
People with T1D and physicians who treat them, multiple Canadian sites, online recruitment
Participants
24 vs 7
Comparison
People with T1D vs Physicians
  • People with T1Dn = 24
  • Physiciansn = 7
Outcome
How risks and benefits of SGLT2i are considered by participants with T1D and physicians (themes)
Methodological detailssemi-structured interviews, multicentre, conventional qualitative content analysis
  • Semi-structured interviews
  • Multicentre
  • Conventional qualitative content analysis

Main finding

As reported in the abstract

Major themes
  • 'Stay in the safe zone': hesitancy to move beyond established therapeutic boundaries
  • 'Feeling the disconnect': divergent lenses between patients and clinicians, tension over who holds expertise in T1D care
  • Ongoing efforts to reconcile risk-benefit trade-offs when considering new therapies
  • Cautiously optimistic search for a path forward, with anticipation and restraint
  • Need for personalization of care (overarching theme)
  • Five major themes

Original publication

Participant and physician perspectives on the use of SGLT2 inhibitors in type 1 diabetes. Diabet Med. Published 4 September 2026. doi:10.1111/dme.70463

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