Automated Insulin Delivery Use Among Preschool-Age Children With Type 1 Diabetes: A T1D Exchange Multicenter Analysis
Authors' conclusion
Real-world use of AID systems in preschool-age children (≤6 years of age) is associated with lower A1c levels and greater potential to achieve the American Diabetes Association (ADA) A1c target range of <7%.
Study context
- Population
- Preschool-age children ≤6 years with T1D, 37 pediatric sites in the T1DX-QI; mean age 4.6 (1.4), 47% female, 31% with public insurance
- Participants
- 3,521 children
- Exposure
- Automated insulin delivery (AID) vs MDI
- Outcome
- HbA1c
Methodological detailsmulticenter, 37 pediatric sites, T1DX-QI
- Multicenter
- 37 pediatric sites
- T1DX-QI
Main finding
As reported in the abstract
HbA1c
Share of cohort AID 48% · MDI 52%
- AID vs MDI: P < 0.0001
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Achieving HbA1c <7% | 1.91 (1.57–2.33) | P < 0.001 | |
| 0.512Odds ratio (log scale) |
- Achieving HbA1c <7% — HbA1c <7% in whole cohort
- 25%
- Achieving HbA1c <7%: multivariable logistic regression adjusted for age, race/ethnicity, diabetes duration, insurance type
Original publication
Automated Insulin Delivery Use Among Preschool-Age Children With Type 1 Diabetes: A T1D Exchange Multicenter Analysis. J Diabetes Sci Technol. Published 23 June 2026. doi:10.
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