Type 1 diabetes

Underrepresentation of females and the elderly with type 1 diabetes in clinical exercise trials: A call to action

Diabet MedPublished Systematic review

Authors' conclusion

Females and the elderly are under-represented in clinical exercise trials conducted in people with T1D.

Study context

Population
Original clinical exercise research articles in individuals with T1D, PubMed, 1985 to 2025
Participants
315 included studies
Outcome
Ratio of male and female participants with T1D in clinical exercise studies; consideration of menstruation; inclusion of the elderly
Methodological detailsstandardized menstrual-status tiering system (Gold, Silver, Bronze)
  • Standardized menstrual-status tiering system (Gold, Silver, Bronze)

Pooled result

As reported in the abstract

Participant sex, age and MC reporting in T1D exercise studies
Studies with mixed-sex population
81%
Overall participant ratio males vs females
57% males vs 43% females
Studies conducted exclusively in females vs in men
six vs 54
Total participants in female-only vs male-only studies
n = 99 vs n = 671
Mean age of participants
29 ± 7 years
Studies conducted solely in post-menopausal females
one
Studies reporting menstrual cycle (MC) status
30
MC-reporting studies graded Bronze
6
MC-reporting studies graded Silver
3
Studies graded Gold
0

Original publication

Underrepresentation of females and the elderly with type 1 diabetes in clinical exercise trials: A call to action. Diabet Med. Published 4 September 2026. doi:10.1111/dme.70468

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