Osteoporosis, bone & mineral

Parathyroid fine‐needle aspiration with parathyroid hormone washout as a preoperative localisation of parathyroid adenoma—A retrospective study

Clin Endocrinol (Oxf)Published Retrospective study

Authors' conclusion

Parathyroid fine-needle aspiration with parathyroid hormone washout was accurate. Immediate, surgical, or delayed complications were not demonstrated in our series. This approach might be considered for selected patients.

Study context

Population
Patients with PHPT who underwent minimally invasive parathyroidectomy after localisation with PTH washout, tertiary referral centre, 2011–2021
Participants
29 patients
Outcome
Short- and long-term safety and efficacy of parathyroid FNA with PTH washout for adenoma localisation
Methodological detailssingle tertiary referral centre, Review of all PTH washout procedures 2011-2021 from electronic medical records
  • Single tertiary referral centre
  • Review of all PTH washout procedures 2011-2021 from electronic medical records

Main finding

As reported in the abstract

Needle-wash PTH levels, times upper limit of serum norm

2.1-112.5

Normocalcemic at end of follow-up after surgery following positive PTH washout

26

90%

Mean follow-up

38.1 months

Observational data: associations, not effects.

Safety

Fibrotic changes and necrosis, no effect on final pathologic diagnosis or surgery course
2 patients
Long-term complications (seeding, parathyromatosis)
0
No immediate procedure complications other than mild neck discomfort

Original publication

Parathyroid fine‐needle aspiration with parathyroid hormone washout as a preoperative localisation of parathyroid adenoma—A retrospective study. Clin Endocrinol (Oxf). Published 7 June 2023. doi:10.1111/cen.14939

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