Diabetes technology

Optimal Data Collection Period for Continuous Glucose Monitoring to Assess Long-Term Glycemic Control: Revisited

J Diabetes Sci TechnolPublished Secondary analysis of pooled continuous glucose monitoring (CGM) data from three studies

Authors' conclusion

Our results suggest that the proposed 10-14 day CGM sampling time may be associated with a high correlation with three-month CGM. However, these estimates are subject to large intersubject bias, which is clinically relevant. Clinicians and researchers should consider using assessments of longer durations of CGM data if possible, especially when assessing time in hypoglycemia or while testing a new treatment.

Study context

Population
T1D patients aged 14–86 years with long-term (90 days) CGM data from three studies
Participants
329 patients3 studies
Comparison
10-day vs 30-day CGM sampling time for estimating 90-day glycemic control
Primary endpoint
Bias in estimating long-term glycemic control (time in range (TIR), time above range (TAR), time below range (TBR)) from short-term CGM sampling

Primary result

As reported in the abstract

Bias in estimating long-term glycemic control

10 days

10% to 47%

30 days

4.9% to 26.4%

P < 0.001

Further findings

Correct classification of patients achieving glycemic targets

Correct classification improved with longer sampling, from 81.5% to 91.9 to 90% to 95.2%

Original publication

Optimal Data Collection Period for Continuous Glucose Monitoring to Assess Long-Term Glycemic Control: Revisited. J Diabetes Sci Technol. Published 5 January 2022. doi:10.1177/19322968211069177

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