Optimal Data Collection Period for Continuous Glucose Monitoring to Assess Long-Term Glycemic Control: Revisited
Authors' conclusion
Our results suggest that the proposed 10-14 day CGM sampling time may be associated with a high correlation with three-month CGM. However, these estimates are subject to large intersubject bias, which is clinically relevant. Clinicians and researchers should consider using assessments of longer durations of CGM data if possible, especially when assessing time in hypoglycemia or while testing a new treatment.
Study context
- Population
- T1D patients aged 14–86 years with long-term (90 days) CGM data from three studies
- Participants
- 329 patients3 studies
- Comparison
- 10-day vs 30-day CGM sampling time for estimating 90-day glycemic control
- Primary endpoint
- Bias in estimating long-term glycemic control (time in range (TIR), time above range (TAR), time below range (TBR)) from short-term CGM sampling
Primary result
As reported in the abstract
Bias in estimating long-term glycemic control
10 days
10% to 47%
30 days
4.9% to 26.4%
P < 0.001
Further findings
Correct classification of patients achieving glycemic targets
- Correct classification improved with longer sampling, from 81.5% to 91.9 to 90% to 95.2%
Original publication
Optimal Data Collection Period for Continuous Glucose Monitoring to Assess Long-Term Glycemic Control: Revisited. J Diabetes Sci Technol. Published 5 January 2022. doi:10. 1177/ 19322968211069177
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