Optimal Sampling Duration for Continuous Glucose Monitoring for the Estimation of Glycemia Risk Index
Authors' conclusion
Though 14 days of CGM sampling duration is optimal for estimation of GRI, 7 days of CGM data may be enough to estimate GRI to monitor change in quality of glycemia with intervention.
Study context
- Population
- Nonpregnant adults with T1D not using hybrid closed-loop system (median age 40 years, 60% females, 20 years of diabetes duration)
- Participants
- 225 adults
- Exposure
- Glycemia risk index (GRI) from various CGM sampling periods vs GRI from all 90 days
- Outcome
- Association (R2) between GRI from various sampling periods and 90-day GRI
Methodological detailsUp to 90 days of CGM data collected
- Up to 90 days of CGM data collected
Main finding
As reported in the abstract
Correlation (R2) with 90-day GRI by sampling duration
R2, 7 days
0.79
R2, 14 days
0.88
R2, 30 days
0.93
Observational data: associations, not effects.
Further findings
- Correlation (r) or R2 for CGM sampling period not different between participants with time <70 mg/dL of <4% and >4%
- Sensitivity analysis
Original publication
Optimal Sampling Duration for Continuous Glucose Monitoring for the Estimation of Glycemia Risk Index. Diabetes Technol Ther. Published 2 December 2022. doi:10. 1089/ dia. 2022. 0401
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