The occurrence of Hospital-Acquired Pneumonia is independently associated with elevated Stress Hyperglycaemia Ratio at admission but not elevated blood glucose
Authors' conclusion
SIH at admission defined as SHR ≥ 1.1, but not the conventional marker of BG ≥ 10 mmol/L, was independently associated with the subsequent onset of HAP, commonly at BG < 10 mmol/L.
Study context
- Population
- Hospitalised subjects with LOS > 1 day, Blood Glucose (BG) within 24 h of admission and recent HbA1c
- Participants
- 5,339 eligible subjects
- Exposure
- Admission Stress Hyperglycaemia Ratio (SHR) ≥ 1.1 vs BG ≥ 10 mmol/L as markers of stress-induced hyperglycaemia (SIH) for Hospital-Acquired Pneumonia (HAP)
- Outcome
- Hospital-acquired pneumonia (HAP)
Methodological detailsobservational, multivariable-adjusted
- Observational
- Multivariable-adjusted
Main finding
As reported in the abstract
HAP · admission
Odds ratio (95% CI)P value
SHR ≥ 1.1
3.04(1.98–4.68)
P < 0.0001BG ≥ 10 mmol/L
0.65(0.41–1.03)
P = 0.0675- Subjects with HAP
- 110 (2.1%)
Observational data: associations, not effects.
Further findings
HAP, using maximum 24-hour values
| OR (95% CI) | P value | ||
|---|---|---|---|
| SHR ≥ 1.1 | 3.37 (2.05–5.52) | P < 0.0001 | |
| BG ≥ 10 mmol/L | 0.96 (0.63–1.46) | P = 0.86 | |
| 0.20.5125Odds ratio (log scale) |
HAP cases with no recorded BG ≥ 10 mmol/L but SHR ≥ 1.1
- HAP cases with no recorded BG ≥ 10 mmol/L but SHR ≥ 1.1
- 40 (36.4%)
Original publication
The occurrence of Hospital-Acquired Pneumonia is independently associated with elevated Stress Hyperglycaemia Ratio at admission but not elevated blood glucose. Diabetes Res Clin Pract. Published 14 October 2023. doi:10.
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