Obesity and the risk of multiple or severe frequent knee pain episodes: a 4-year follow-up of the ELSA-Brasil MSK cohort
Authors' conclusion
These results provide further support that overweight and obesity are important contributors to the incidence and worsening of FKP, and that weight management must be prioritized in multidisciplinary knee pain prevention and treatment programs to reduce the burden of musculoskeletal disorders.
Study context
- Population
- Civil servants in the ELSA-Brasil MSK cohort; 54.2% female, mean age 55.8 (SD 8.8) years; incidence cohort (no knee pain at baseline) and prognosis cohort (knee pain at baseline)
- Participants
- 2,644 participants
- Exposure
- Obesity and overweight vs normal weight
- Outcome
- Frequency (one or multiple) and severity (non-severe or severe) of frequent knee pain (FKP) episodes
- Follow-up
- 4 years
Methodological details4-year follow-up, multinomial logistic regression adjusted for confounders, Knee pain assessed at baseline face-to-face interviews (2012-2014) and four yearly telephone follow-ups (2015-2019), Disabling frequent knee pain (FKP) episodes or those of moderate to very severe intensity classified as severe
- 4-year follow-up
- Multinomial logistic regression adjusted for confounders
- Knee pain assessed at baseline face-to-face interviews (2012-2014) and four yearly telephone follow-ups (2015-2019)
- Disabling FKP episodes or those of moderate to very severe intensity classified as severe
Main finding
As reported in the abstract
FKP episodes with obesity
- Incidence cohort (n = 1896): one FKP episode, obesity, OR
- 1.63 (1.13-2.37) (95% CI)
- Incidence cohort: multiple FKP episodes, obesity, OR
- 2.61 (1.71-3.97) (95% CI)
- Incidence cohort: non-severe FKP episodes, obesity, OR
- 1.72 (1.04-2.84) (95% CI)
- Incidence cohort: severe FKP episodes, obesity, OR
- 2.10 (1.50-2.95) (95% CI)
- Prognosis cohort (n = 748): multiple FKP episodes, obesity, OR
- 2.54 (1.60-4.05) (95% CI)
- Prognosis cohort: severe FKP episodes, obesity, OR
- 2.31 (1.49-3.59) (95% CI)
Observational data: associations, not effects.
Original publication
Obesity and the risk of multiple or severe frequent knee pain episodes: a 4-year follow-up of the ELSA-Brasil MSK cohort. Int J Obes (Lond). Published 19 September 2023. doi:10.
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