Nutritional status as independent prognostic factor of outcome and mortality until five years after hip fracture: a comprehensive prospective study
Authors' conclusion
As baselline nutritional status is a strong independent prognostic factor for clinical outcome after hip fracture, affecting even five-year survival
Study context
- Population
- Subjects aged 55+ years with a hip fracture from a previously published RCT
- Participants
- 152 subjects
- Exposure
- Impaired vs normal baseline nutritional status
- Outcome
- Multiple clinical and functional outcomes over 6 months; new fractures and survival over 5 years post-fracture
Methodological detailssecondary analysis of a randomised controlled trial cohort, multivariable linear, logistic and Cox regression
- Secondary analysis of a randomised controlled trial cohort
- Multivariable linear, logistic and Cox regression
Main finding
As reported in the abstract
Prognostic value of impaired baseline nutritional status
- Postoperative complications, OR (95% CI 1.01-3.98), p = 0.047
- 2.00
- Discharge location (home vs. rehabilitation clinic), OR (95% CI 0.18-0.98), p = 0.044
- 0.41
- Hospital readmission, OR (95% CI 1.70-12.4), p = 0.003
- 4.59
- Total LOS, HR of being discharged (96%CI 0.44-0.89), p = 0.008
- 0.63
- 5-year mortality, HR (95% CI 1.53-10.2), p = 0.005
- 3.94
- New fractures, 5y-HR (95% CI 0.34-2.24), p = 0.769
- 0.87
Observational data: associations, not effects.
Further findings
Baseline associations of impaired nutritional status
- Significantly associated with physical disability, depression, impaired cognition and lower quality of life
Physical disability trajectories · baseline to 6 months
- Three nutritional status categories followed almost parallel trajectories, without complete recovery; further deterioration in malnourished subjects from 3 to 6 months
Original publication
Nutritional status as independent prognostic factor of outcome and mortality until five years after hip fracture: a comprehensive prospective study. Osteoporos Int. Published 17 May 2024. doi:10.
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