Osteoporosis management in adults with schizophrenia following index hip fracture event: a 10-year population-based retrospective cohort study, Ontario, Canada
Main finding · Osteoporosis testing or treatment (composite)Result — go to the resultEstimate 0.795 CI 0.721–0.877Authors' conclusion
In this population-based retrospective cohort study, a schizophrenia diagnosis among hip fracture patients was associated with a lower incidence of testing or treatment, after accounting for mortality, and several enabling and predisposing factors.
Study context
- Population
- Individuals aged 66–105 years with index hip fracture between fiscal years 2009 and 2018, Ontario, Canada1,890 (3.6%) with schizophrenia
- Participants
- 52,722 individuals
- Exposure
- Hip fracture patients with vs without schizophrenia
- Schizophrenian = 1,890
- Outcome
- Composite of:
- Pharmacologic prescription for osteoporosis
- A bone mineral density (BMD) test
Methodological detailspopulation-based, health administrative databases, Fine-Gray subdistribution hazard regression, mortality as competing event
- Population-based
- Health administrative databases
- Fine-Gray subdistribution hazard regression, mortality as competing event
Main finding
Osteoporosis testing or treatment (composite)
Estimate
0.795
CI 0.721–0.877
As reported in the abstract
Observational data: associations, not effects.
Further findings
Long-term care residents
standardized difference 0.59
Frail
standardized difference 0.54
Without a primary care provider
standardized difference 0.18
Original publication
Osteoporosis management in adults with schizophrenia following index hip fracture event: a 10-year population-based retrospective cohort study, Ontario, Canada. Osteoporos Int. Published 17 May 2024. doi:10. 1007/ s00198-024-07123-3
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