Determination of the Combined Effects of Asian Herbal Medicine with Calcium and/or Vitamin D Supplements on Bone Mineral Density in Primary Osteoporosis: A Systematic Review and Meta-Analysis
Errata to this article were published (Osteoporos Int, Jul 2024 ↗ · Mar 2025 ↗)
Pooled result · Lumbar BMDResult — go to the resultDifference 0.08 g/cm² 95% CI 0.06–0.10Authors' conclusion
Our data suggest that combining of HM and supplements tends to be more effective in improving BMD in primary OP than supplements alone.
Study context
- Population
- Primary osteoporosis patients; Randomized controlled trials (RCTs) from 5 databases published until August 31, 2022
- Participants
- 4,889 patients52 RCTs
- Comparison
- Herbal medicine plus calcium (Ca) and/or Vit.D supplements vs supplements alone
- Outcome
- Bone mineral density (BMD) score
Methodological detailsRoB 2.0 risk of bias assessment
- RoB 2.0 risk of bias assessment
Pooled result
Lumbar BMD
Difference
0.08 g/cm²
95% CI 0.06–0.10
P < 0.001
HM + supplementsvs Supplements alone
difference 0.08 g/cm² (95% CI 0.06–0.10); P < 0.001
As reported in the abstract
Further pooled results
| Outcome | Difference (g/cm²) (95% CI) | P value | |
|---|---|---|---|
| Femoral neck BMD19 RCTs; I2 = 92% | 0.06 (0.04–0.08) | P < 0.001 | |
| −0.0500.050.1Difference, g/cm² (linear scale) |
Original publication
Determination of the Combined Effects of Asian Herbal Medicine with Calcium and/or Vitamin D Supplements on Bone Mineral Density in Primary Osteoporosis: A Systematic Review and Meta-Analysis. Osteoporos Int. Published 13 March 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →