Newborn screening for congenital hypothyroidism in France: a study of current professional practices
Authors' conclusion
This nationwide survey highlights substantial heterogeneity in congenital hypothyroidism screening practices across France. Variations in TSH thresholds, thyroxine measurement, and preterm infant management may impact diagnostic consistency and equity. Harmonization efforts based on evidence are needed to optimize neonatal screening performance nationally.
Study context
- Population
- All 16 French Regional Neonatal Screening Centers (congenital hypothyroidism screening), 2024100% response rate
- Participants
- 16 participants
- Outcome
- Current practices of Regional Neonatal Screening Centers and their conformity with national recommendations
Methodological detailsdescriptive survey, structured online questionnaire, nationwide
- Descriptive survey
- Structured online questionnaire
- Nationwide
Main finding
As reported in the abstract
- Centers reporting deviations from national recommendations
- 9 (56%)
- Centers applying alternative TSH retesting or referral thresholds
- 5
- Centers measuring thyroxine on first dried blood spot for intermediate TSH levels
- 4
- Centers retrospectively evaluating thyroxine approach
- 1
- Centers with specific resampling protocols for preterm infants
- 3
- Centers using gestational age-adjusted TSH thresholds
- 0
Observational data: associations, not effects.
Original publication
Newborn screening for congenital hypothyroidism in France: a study of current professional practices. Eur Thyroid J. Published 25 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →